Features and Benefits:

• 6 different volumes: 30 L, 50 L, 75 L, 100 L, 150 L, 200 L.
• 3:1 H/D ratio.
• Parts in contact with the culture AISI 316 L, other parts AISI 304.
• Finishing: mirror polished (internal and external).
• Compact design.
• Double jacket (side/bottom), for higher heat transfer efficiency and optimal temperature control.
• Bacteria (Toro sparger, Rushton impellers) and cell cultures (Sintered sparger, Marine impellers) configurations available.
• Welded baffles.
• Wide range of measurement and control options for cell cultures and aerobic/anaerobic microbial fermentations, including temperature, pH, dO​2​, dCO​2​, redox, antifoam, level, conductivity, weight, cell density (total cells, viable cells).
• Modbus digital sensors.
• Suitable for batch, fed-batch and continuous processes.
• Stainless-steel industrial PCS ​LEM_2​, with a selectable number of peristaltic pumps, choosing between Watson Marlow WM 114, WM 313 and WM 520.
• Powerful and accurate (1 RPM) brushless motor, mounted on top.
• Different gas mixing strategies with a selectable number of TMFCs or solenoid valves, for air, O​2​, CO​2​ and N​2​.
• SALAS (Solaris Sterile Liquid Addition System) included in the standard configuration.
• Up to 2 steam bridges (re-sterilizable diaphragm valves for inoculum/feedings) can be added in option (with manual or automatic sterilization control).
• Non-SIP sampling and harvest valves are included in the standard configuration. Steam SIP lines can be added in option. Manual or automatic sterilization.
• TK connection.
• Tri-Clamp stainless steel piping.
• Single mechanical seal. Double mechanical seal, with automatic lubrication though steam condensate loop available in option.
• Thermoregulation loop consisting of n.2 heat exchangers and recirculating pump.
• Separate drains: cooling water return, condense drain to waste, hot condense return.
• Gravimetric flow control (option): feed rates controlled through weight measurement.
• CIP system options: n. of removable spray balls or integrated system (recirculating pump + n. of removable spray balls + software automation). N. of spray balls depending on vessel volume.
• Optional vessel empty sterilization.

Automation and Software:

• Innovative SCADA software​ ​LEONARDO​ ​3.0​: a smart and user-friendly controller designed to provide a high level of automated management of the fermentation/cultivation processes.
• 24” coloured touch screen industrial HMI.
• Included in the equipment supply.
• Data extraction in .csv format.
• Remote access via PC, tablet or smartphone, with QR code scanning or dedicated portal.
• Remote control for after sale assistance.